Contraindicated (one)pentobarbital will lessen the extent or outcome of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is responsible for the formation and elimination of cariprazine's Lively metabolites.
Check Intently (1)pentobarbital will decrease the level or outcome of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Lack of, or decreased reaction to tofacitinib may manifest when coadministered with strong CYP3A4 inducers
Use Warning/Watch. CYP3A4 inducers might enhance the metabolism of clopidogrel to its active metabolite. Watch patients for likely increase in antiplatelet effects when CYP3A4 inducers are used in combination with clopidogrel
fentanyl intranasal and pentobarbital both enhance sedation. Stay away from or Use Alternate Drug. Restrict use to individuals for whom alternate treatment possibilities are inadequate
pentobarbital will minimize the extent or result of fosphenytoin by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep an eye on.
pentobarbital will lower the extent or result of temsirolimus by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Monoamine oxidase inhibitors (MAOI) may possibly inhibit barbiturate metabolism and extend barbiturate effects; keep track of closely
pentobarbital will reduce the level or influence of cilostazol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the level or impact of ritonavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the level or influence of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye get more info on Intently. Suggested atogepant dosage with concomitant use of powerful or reasonable CYP3A4 inducers is thirty mg or sixty mg qDay.
pentobarbital will decrease the extent or influence of atazanavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will reduce the extent or effect of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Mysterious.
pentobarbital will lower the extent or result of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Ladies must not opt for estradiol valerate/dienogest as their contraceptive even though working with sturdy CYP3A4 inducers as a result of prospective decrease in contraceptive efficacy.
pentobarbital will decrease the level or influence of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Prevent coadministration if possible. Check for lessened pimavanserin efficacy. An increase in pimavanserin dosage can be needed.